Formation - Extraction of Ion Pair Complexes of [PdI4]-2 and[BiI4]-1 with Trifluoperazine Hydrochtoride (TFPri) Drug andDetermination by Molecular Absorption Spectroscopy

Abstract

This Study includes the determination of (TFPH) drug via the formation of ion association pair with [pdly]? and with [Bily]" in aqueous phase . The analytical results obtained are as follow: the optimum pH is 5 and 4, reaction time is immediate and 5 minutes, mixing time 3 and 4 minutes for the two ion pair respectively. The statistical and other analytical results for the first ion pair in the concentration range (6- -40ppm) were as follow: the detection limit is 0.228 ppm, molar absorption coefficient is 2.3635x10* liter mole™ em™ at 297nm . For Bily — TFPH ion pair at 292 nm, the results in the concentration range (0.2-18ppm) ere as follow: detection limit is 0.0030 ppm , and molar absorption coefficient is 3.747 x 10° liter mole” cm™ . This method was applied to Salabid pharmaceutical preparation with percentage recovery of not less than 98.5%