Effect of hydrocortisone and olive oil on phagocytes

Abstract

This study organized to realize the side effect of hydrocortisone therapy which administrated by thigh muscle injection on phagocytic cells, and inhibit their functions. Fifteen laboratory male white mice was distributed into three groups used in this study , each group consist of five animals . 1st group administrated by normal saline orally for ten days, while 2nd group injected in thigh muscle by 1mg/kg of the therapy for ten days, and the 3rd group injected in thigh muscle by 1mg/kg of the therapy for ten days then administrated orally by 0.5 ml / 100 g of olive oil for anther ten days.The Results of the study agree with other studies and investigate side effect of the therapy which cause inhibition to the activity of phagocytic cells and decrease in their number in 2nd group, whenever in 3rd group the study discover the benefit of olive oil to reactivate the whole of immune system and especially the phagocytic cells and increase their number.