Effect of Tonsillectomy on Antistreptolysin O (ASO) Titer
DOI:
https://doi.org/10.25130/tjphs.2023.17.1.3.22.29Abstract
Abstract
Recurrent attacks of tonsillitis are a common worldwide problem and the best treatment of choice after failure of medical therapy is a tonsillectomy. The large numbers of patients that presented with recurrent attacks of tonsillitis and associated with high antistreptolysin O (ASO) titer level due to group A beta hemolytic streptococcal (GABHS) tonsillitis will have serious complications as glomerulonephritis and rheumatic fever. The aim of study: to evaluate the effect of tonsillectomy on elevated ASO titer.
Patients and methods: Prospective non-randomized clinical study was performed at Al-Jumhory teaching hospital, Mosul, Iraq; for the period from January 2021 to January 2022. that included seventy patients for whom tonsillectomy was indicated. There were 45 females and 25 males, the age range from 3 to15 years old and the mean age was7.63
year. Positive throat swab for group A beta hemolytic streptococcal (GABHS) and elevated ASO titer level (≥200 IU/ml). Postoperative follow up of the patients were processed for six months.
Results: seventy patients included in the study, presented with recurrent attacks of tonsillitis, with positive throat swab for GABHS and elevated ASO titer level (≥200 IU/ml), age between 3 to 15 years old .Follow up of the patients for six months after tonsillectomy had been shown that there is a significant decrease in ASO titer level in comparison to preoperative level measures (p <0.001 )
Conclusion: The most important conclusion from the result of our study that tonsillectomy lead to significant reduction in ASO titer level.

Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Tikrit Journal of Pharmaceutical Sciences

This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open-access journal, and all journal content is available for readers free of charge immediately upon publication.