Effect of Sex Steroid Hormone (Estrogen) on Bone Mass Density in Men

Abstract

Osteoporosis is a systemic and metabolic skeletal disease characterized by reduced bone mass .It is a growing health problem in men as well as women. The objective of this work is to demonstrate the role of sex steroid hormone, estrogen (E2), in maintaining bone mass. Spine bone mass density (BMD) was measured using Dual Energy X-ray Absorptiometry (DEXA) for (111) subjects and patients with osteoporosis and serum levels of estradiol were measured . The results show a highly significant(p<0.001) correlation between serum level of estradiol and spine BMD in young , middle age , and elderly men .The present study concluded that estrogen is important in maintaining BMD in men .