Certain Serum Enzymes Study of P-Thalassaemia Major Among Mosul Population

Abstract

Ninety-seven blood samples of the P-thalassaemia major were collected from patients registered in Mosul thalassemic center (lbn Al-Ather pediatric hospital ) for the period 2001-2002, distributed in 52 males and 45 females aged 3.5-24.0 yrs old, and 87 blood samples of apparently healthy volunteers aged 3.5-24.0 yrs old too, distributed in 56 males and 31 females for the same aged and the period time . Hb cone., sGPT, sGOT, and ALP values were determined in addition to the age estimation for the two trails.
Statistical analysis, show there were significant differences (p<0.05) within Hb cone. of the normal individuals aged 3.5-6.0 and 18.0-24.0 yrs old. The Hb means cone. of both P-thalassaemia major and normal (control) were directly proportional to the sGPT and sGOT. while the Hb mean cone. of the P-thalassaemia major only was directly proportional to the ALP. The sGPT (17.64 u/1), sGOT (13.99 u/1), and ALP (16.43 u/1) values of the P-thalassaemia major was higher than that values ( 4.74 u/1 , 10.95 u/1, and 4.65 u/1 respectively) of the normal individuals .