Adenosine Deaminase values of serum and erythrocytes in patients with Cutaneous Leishmaniasis and healthy subjects in Nineveh state population

Abstract

Cross sectional, hospital based study was carried out on 46 Cutaneous Leishmaniasis patients (25 males and 21 females) and fifty four healthy volunteers were investigated to serve as normal subjects. Serum and erythrocytes Adenosine Deaminase activity was assessed spectrophotometerically by using colorimetric method. Serum and erythrocytes Adenosine Deaminase activity of Leishmaniasis-patienats were highly significant (p< 0.005) and higher (38.8  ± 2.5 and 188.1 ± 23.3 U/L) than that values of healthy individuals ( 14.8 ± 1.4 and 64.1 ± 7.5 U/L respectively). No significant difference values were found in blood ADA activity according age and sex. In conclusion serum and erythrocytes ADA values may be used in the follow up of patients with Cutaneous Leishmaniasis together with clinical and other laboratory findings.